Profile of urinary dapsone/creatinine ratios after oral dosage with dapsone
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چکیده
منابع مشابه
Quantification of Proteinuria with Urinary Protein to Osmolality Ratios in Children
Background: The ratio of urine protein to urine osmolality has recently been suggested as an accurate method to determine proteinuria. Objective: We studied the correlation of urine protein to urine osmolality ratio with 24-hr urinary protein excretion. Methods: 150 children aged 0.11–17 years admitted to the Department of Pediatric Nephrology were included in this study. Early morning urine s...
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Pharmacokinetic profiles in rats after intravenous, oral, or dermal administration of dapsone.
Dapsone is a potent anti-inflammatory and antibacterial agent that has been used extensively in the oral treatment of leprosy and dermatitis herpetiformis. This study compared the pharmacokinetic profile of dapsone in rats given a single oral or i.v. 12 mg/kg dose (n = 8/group) or a single dermal application of 12 or 60 mg/kg (n = 12/group) in an aqueous gel application medium containing 10 or ...
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متن کاملUrinary metabolic profile of 19-norsteroids in humans: glucuronide and sulphate conjugates after oral administration of 19-nor-4-androstenediol.
19-Nor-4-androstenediol (NOL) is a prohormone of nandrolone (ND). Both substances are included in the WADA List of Prohibited Classes of Substances and their administration is determined by the presence of 19-norandrosterone (NA) with the urinary threshold concentration of 2 ng mL(-1). Routine analytical procedures allow the determination of NA excreted free and conjugated with glucuronic acid,...
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ژورنال
عنوان ژورنال: Leprosy Review
سال: 1980
ISSN: 0305-7518
DOI: 10.5935/0305-7518.19800021